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Sexual assault: assessment and care

Trauma-informed assessment and care after sexual assault, from first response to forensic evidence, prophylaxis, follow-up, consent and reporting.

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In one minute

  • Sexual assault is a medical, forensic and psychological emergency. It can leave injuries, pregnancy, infection, and severe distress, and in most legislations it is also a crime. Your first job is to look after the person who has been hurt: safety, pain, bleeding, pregnancy and infection prevention, and dignity come before any paperwork.
  • Most assailants are known to the survivor. People of any gender and age can be assaulted, and men, adolescents, older adults and people with disabilities are often missed.
  • The evidence that later supports a legal case degrades quickly. Forensic specimens and photographs must be taken as early as possible, with the person's consent, by a clinician trained to collect them.
  • Time-critical treatments are emergency contraception within 5 days, HIV post-exposure prophylaxis within 72 hours (best within 24 hours), hepatitis B vaccination at the first visit, and STI prophylaxis.
  • A normal examination does not exclude assault. Injuries are often absent, and co-operation is never a reliable clue.
  • Everything you do must be consented, private, trauma-informed and non-judgemental, and documented in the person's own words.

Learning objectives

By the end of this page you should be able to:

  1. Provide trauma-informed first-line care to a person presenting after sexual assault, in a way that supports both their health and their choices about reporting. [2]
  2. Take a forensic and clinical history that captures the information needed for care, for risk assessment and (with consent) for evidence, without re-traumatising the person.
  3. Collect and preserve forensic specimens correctly, knowing the time windows within which each type of specimen remains useful.
  4. Decide when emergency contraception, HIV post-exposure prophylaxis, hepatitis B and HPV vaccination and empiric STI treatment are indicated, and name the regimens, doses, routes and follow-up tests.
  5. Obtain informed consent, protect confidentiality and follow the reporting requirements of your own setting without imposing your own judgement.
  6. Document the encounter, plan follow-up and safety, and refer to the services a survivor is likely to need.

Definition and scope

DefinitionSexual assault

Sexual assault is any sexual act, attempt to obtain a sexual act, unwanted sexual comment or advance, or other act directed against a person's sexuality, using coercion, by any person regardless of their relationship to the victim, in any setting. [1] Rape is non-consensual penetration of the vagina, anus or mouth by a penis or other object. In practice the two terms overlap, and these guidelines use "sexual assault" for the whole range of acts. The words used by the individual and by the law in your own country may differ.

This page is about the care of an adolescent or adult who presents after an assault. Child sexual abuse requires the specialist paediatric and safeguarding services of your setting and is mentioned here only for referral and consent purposes. The medical parts of the WHO definition apply to both men and women: most victims are female and most perpetrators male, but men are assaulted too and are often not asked. [1]

The scope of this page is broader than the CDC 2021 STI chapter, which concentrates on identifying and preventing infection. [4] STI prevention is only one part of care. The medico-legal side, the pregnancy and psychological dimensions, are covered here using the WHO 2003 medico-legal guidelines and the WHO 2013 clinical guidelines for responding to sexual violence. [1][2]

Sexual assault is a crime in most jurisdictions and a reportable injury in many. The law on age of consent, mandatory reporting, confidentiality, access to abortion, and evidentiary privilege differ between countries and sometimes between regions of the same country. What follows are the principles that are widely accepted; apply them inside your own legal framework and consult a clinician, a specialist or a lawyer with experience in this field when in doubt. [1]

Why the first hours matter

A person who has been assaulted has three separate sets of needs that all start at once: urgent medical care, evidence that may be lost with washing and delay, and time-critical prophylaxis (emergency contraception and HIV prophylaxis). [1] At the same time they may be frightened, in shock, and deciding whether they want the police involved at all. Treating these as competing demands is a common mistake. The safe sequence is:

  1. Safety and urgent medical treatment for injury or distress.
  2. First-line support while consent is obtained.
  3. Time-critical steps that have windows (evidence collection, emergency contraception, HIV prophylaxis, hepatitis B and HPV vaccination).
  4. Everything else (STI prophylaxis, full documentation, follow-up).

The WHO 2013 guidelines group the medical work of the first five days into a defined set of early interventions. [2] Acting early matters more for evidence than for most treatment: once the person has washed, evidence may be lost, while treatment can be started later within the windows set out below.

Who it applies to

Everyone who has been sexually assaulted, whatever their age, gender, orientation, disability, migration status or substance use. Some groups need specific attention:

  • Women and adolescents. Reproductive-age survivors need pregnancy assessment and emergency contraception. [4]
  • Men and boys. They may have anal or oral exposure and are often less likely to be offered prophylaxis or support. The same health steps apply.
  • Older adults and those with cognitive impairment. Consent capacity and safeguarding must be assessed carefully; abuse may be ongoing and disguised as care.
  • People in conflict, displacement and humanitarian settings. The WHO/UNHCR protocols and the e-learning programme that the WHO 2013 guidelines refer to are written for these settings. [2]
  • Sex workers and people who inject drugs. HIV risk and barriers to care are high; the same stepped care applies, and blame must be avoided.

Services should be usable around the clock; where a clinic cannot staff 24 hours, there must be a clear route for survivors to be seen elsewhere with a reliable referral. [1]

Stepwise approach

The following order is a teaching skeleton, not a rigid protocol. Adapt it to the person in front of you and to local services.

  1. Receive and make safe. Greet by name, offer a private space, and treat medical threats (bleeding, airway, strangulation, head injury, poisoning) first.
  2. First-line support. Sit down, introduce yourself and your role, explain what can be offered before talking about the assault. Listen, validate, ask about safety and immediate needs. [2]
  3. Consent. Explain each option separately: medical care, forensic examination, evidence release to police, photographs, samples. Consent can be given, refused or postponed separately for each, and can be withdrawn.
  4. Risk and needs assessment. Time of assault, acts, injuries, pregnancy, HIV and STI risk, contraception, mental state and safety.
  5. Examination when consented and needed, from general injuries to the genito-anal area, not the reverse.
  6. Evidence collection within windows, with chain of custody.
  7. Prophylaxis and treatment for STI, pregnancy, HIV and hepatitis B/HPV.
  8. Documentation in the person's own words, with body maps.
  9. Follow-up and referral (medical, psychological, social, legal), including a safety plan.

Clinical pearlThe order can change, but the windows do not

If the person is bleeding from trauma or has a head injury, treat that first even though it delays forensic sampling. If pregnancy prophylaxis or HIV prophylaxis is running out of time, it can be started before a full examination or completed forensic bundle, provided the records say why.

Trauma-informed history

Take the history in a private room with the door closed, with a chaperone if the person wants one and a trained interpreter if their first language or sign language is not yours. Avoid repeating the story in front of relatives or police. Use the person's own words where possible and ask permission before touching.

Start with health, not with the assault. Ask about:

  • when the assault occurred (date and approximate time), and when the person last washed, changed, urinated or defaecated, which affects evidence recovery;
  • what happened in clinical terms (genital, anal and/or oral penetration; ejaculation; use of condoms, if known; use of objects, fingers or foreign bodies; violence, restraint, strangulation, bites, weapons, and injuries they are aware of);
  • last menstrual period, usual contraception, parity and whether pregnancy is possible or wanted;
  • current medications, allergies, medical conditions (including renal or liver disease relevant to HIV prophylaxis), hepatitis B and HPV vaccination status, and any current STI or HIV risk behaviour or diagnosis;
  • the assailant's known or possible HIV status and risk factors (for example injecting drug use or sex with men), the number of assailants, bleeding during the assault, and whether any site of exposure was mucosal with ejaculate;
  • drugs or alcohol: an alteration in consciousness raises drug-facilitated assault and needs full resuscitation facilities and blood and urine samples taken as soon as possible; [1]
  • previous sexual violence, intimate partner violence, and ongoing safety at home;
  • mental state, suicidal thoughts, self-harm, and who to contact if the person leaves alone.

Adolescents. The same steps apply, but a healthcare provider trained in paediatric care should be involved, and consent, capacity and safeguarding rules for minors in your jurisdiction apply from the first minute. Do not perform an intimate examination on a child unless you are appropriately trained; refer to the child sexual abuse service.

History of the examination itself. A forensic examination is not the same as a medical one. Explain what each involves and what it could add, and record consent separately. [1]

Examination

Consent must be obtained for the examination and, separately, for the release of the findings to third parties. [1] Work with a chaperone of the person's choosing. Examine general injuries before the genito-anal area, not after, so the person is not lying exposed while waiting.

General examination:

  • vital signs, including oxygen saturation if there is any doubt about the airway or breathing after strangulation or smothering;
  • head, neck, mouth and teeth, especially in oral assaults and in restraint;
  • all skin for bruises, lacerations, burns, bite marks and patterns of assault (photograph with a scale, with written consent);
  • limbs and trunk for fractures or soft-tissue injury;
  • neurological examination if head injury, loss of consciousness or strangulation is reported, and a low threshold for imaging.

Genito-anal examination should be done only by a clinician trained in sexual assault care, and only if clinically indicated or with consent for forensic purposes. A speculum examination is not automatic: it is particularly relevant if there is vaginal or pelvic pain, bleeding, a suspected foreign body, or if forensic samples are needed from the endocervical canal. Pressured or painful examinations re-traumatise and may be declined; record refusal without judgement. [3]

Baseline tests at the first visit (individualise, per CDC guidance): [4]

  • NAAT for Chlamydia trachomatis and Neisseria gonorrhoeae at the sites of penetration or attempted penetration;
  • for women, NAAT for Trichomonas vaginalis from urine or vaginal specimen; a point-of-care or wet mount test with vaginal pH and whiff test if vaginal discharge, malodour or itching is present;
  • for men who have sex with men, screening for C. trachomatis and N. gonorrhoeae if receptive oral or anal sex in the preceding year (regardless of whether those sites were involved in this assault), and anoscopy if anal penetration is reported;
  • serum testing for HIV, hepatitis B and syphilis;
  • pregnancy test in anyone who could be pregnant.
Table 1. Time windows after the assault for collecting forensic specimens (WHO 2019 training curriculum)
SiteTypical window after the assault
Skin, including bite marks72 hours
Mouth12 hours
Vaginaup to 5 days
Anus48 hours
Clothing and other objectsas soon as possible
These are teaching windows; the earlier a specimen is taken, the more useful it is. Collect as much as is appropriate and permitted, with the person's consent, and follow the chain of custody of your service.

After 5 days a vaginal sample may still be worth taking in selected cases, and some injuries (bruising, for instance) become more visible after a few days, so a second, documented examination is sometimes needed. [3] The person should be told this and offered it.

Decision points with thresholds

The table brings together the time-critical decisions. Use it as a checklist at triage and again before discharge.

Table 2. Time-critical decisions after sexual assault
DecisionWindowWhat to do
Forensic specimensSkin 72 h; mouth 12 h; vagina 5 days; anus 48 hCollect, document and chain-of-custody with consent. [3]
Emergency contraceptionLevonorgestrel: under 72 h (may be used 72-96 h off label); ulipristal acetate or copper IUD: under 120 hOffer all methods; copper IUD is most effective.
HIV post-exposure prophylaxisAs soon as possible, within 72 h (best within 24 h)Start a 28-day 3-drug regimen if indicated.
Hepatitis B prophylaxisFirst dose at the initial visitVaccine, plus HBIG if assailant is known HBsAg positive.
HPV vaccinationFirst dose at the initial visit for ages 9-26Continue the schedule at follow-up. [4]
Empiric STI treatmentAt the initial visitCeftriaxone + doxycycline (+ metronidazole for women).
Pregnancy test if no contraceptionRepeat when a period is missed after the assaultOffer counselling and referral.

Management at each step

STI prophylaxis

Compliance with follow-up is poor after sexual assault, so the CDC 2021 guidelines recommend presumptive treatment at the first visit, rather than waiting for test results. [4] This is treatment rather than true prophylaxis, but it is standard practice in many settings because failure to treat risks pelvic infection and complications.

The recommended regimen for adolescent and adult female survivors is: [4]

  • Ceftriaxone 500 mg intramuscularly, single dose, plus
  • Doxycycline 100 mg by mouth twice daily for 7 days, plus
  • Metronidazole 500 mg by mouth twice daily for 7 days.

For males the regimen is ceftriaxone 500 mg intramuscularly plus doxycycline 100 mg by mouth twice daily for 7 days. [4] For anyone weighing 150 kg or more, give 1 g of ceftriaxone. [4] Tell people to expect possible gastric side effects and to abstain from sexual intercourse until treatment is completed. [4]

If they decline presumptive treatment, or if your service has excellent follow-up, a strategy of treating only confirmed infection is acceptable and prevents over-treatment; document the discussion and the plan. The UK approach, for instance, treats prophylaxis as a selective option rather than a routine one. [6]

Pregnancy prophylaxis: emergency contraception

Reproductive-age survivors who do not already use reliable contraception should be offered emergency contraception at the first visit; discuss it even if the test is negative, because ovulation may not have occurred yet. [4]

There are three methods, summarised in Table 3. [6][7]

Table 3. Emergency contraception after sexual assault
MethodDose or actionTime windowNotes
Copper IUDInsert as soon as possibleUnder 5 days (120 h) from first unprotected intercourse, or under 5 days after earliest estimated ovulationCan become ongoing contraception.
Levonorgestrel1.5 mg orally, single doseLicensed under 72 h; may be used 72-96 h off label with falling efficacyIneffective after ovulation; reduced efficacy with higher body weight or BMI (consider double dose or ulipristal). [6][7]
Ulipristal acetate30 mg orally, single doseUnder 120 h (5 days)More effective than levonorgestrel; first-line oral option for intercourse 96-120 h earlier. [6]
The copper intra-uterine device is the most effective method of emergency contraception and the only one that works reliably after ovulation. FSRH 2017, amended 2023; BNF.

Practical points: [6][7]

  • Women and adolescents requiring emergency contraception after assault should be offered all methods, including the copper IUD. [6]
  • A copper IUD is recommended for all at-risk survivors within the window because it is the most effective method. A pregnancy rate that the FSRH describes as extremely low is achieved if it is fitted within 5 days of unprotected intercourse or of the estimated day of ovulation. [6] Antibiotic cover for STI should be considered if a copper IUD is fitted, because of the risk of ascending infection. [6]
  • If the person chooses a copper IUD after assault but wants or needs a forensic examination, defer insertion until after the forensic examination, and give oral emergency contraception in the meantime in case fitting is delayed. [6]
  • Discuss the option of forensic examination and the timeframe for collecting forensic samples when planning the method. [6]
  • If oral methods are used at higher body weight, efficacy may be reduced; the evidence favours ulipristal acetate or a double 3 g dose of levonorgestrel at higher body mass index, but which is better is not known. [7]
  • If a period has not occurred by 3 weeks after the assault, arrange a pregnancy test and discuss the options.

If a pregnancy test is already positive after the assault, stop and discuss continuation, termination where lawful and desired, and in some systems sampling for paternity testing as part of care. [1][3]

HIV post-exposure prophylaxis

HIV transmission per act of vaginal intercourse in consensual sex is estimated at about 0.08% and of receptive anal intercourse at about 1.38%. [4] Assault may carry a higher risk than consensual sex because of bleeding, mucosal trauma, multiple assailants and possible assailant HIV status. [4] HIV infection has been documented in people whose only known risk factor was sexual assault, but it is uncommon. [4] Base the recommendation on the characteristics of the assault and the assailant rather than on worry alone.

If HIV post-exposure prophylaxis (PEP) is being considered: [4][5]

  • start as soon as possible and no later than 72 hours after exposure; the first 24 hours are preferable. [4][5]
  • do not delay the first dose while waiting for laboratory results. [5]
  • give a 28-day course of a three-drug regimen. [4][5]
  • preferred regimens for most adults and adolescents (CDC 2025): bictegravir/emtricitabine/tenofovir alafenamide once daily, or dolutegravir plus tenofovir (alafenamide or disoproxil fumarate) plus emtricitabine or lamivudine. [5]
  • consult an HIV specialist if the survivor is a child, pregnant, has renal or liver disease, is already taking PrEP, or there is concern about resistance.
  • take baseline serum creatinine, AST and ALT. [4]
  • test for HIV at baseline, at 6 weeks and at 3 months, using methods that detect acute infection when a window-period infection is suspected. [4][5]
  • give a first course of 3-7 days (a starter pack) with a prescription for the rest of the 28 days, or the entire 28-day supply at the first visit, which improves adherence; ensure the person can actually obtain the remainder. [4]
  • arrange an early follow-up visit at 24 hours to discuss results, side effects and adherence, and follow-up at 4-6 weeks and 12 weeks after exposure. [4][5]
  • discuss that most people tolerate these regimens without serious adverse effects, and counsel about ongoing risk and referral for HIV pre-exposure prophylaxis (PrEP) afterwards. [4]
  • practical decisions can be supported by the National Clinician's Post-Exposure Prophylaxis Hotline (PEP Line, 888-448-4911) in the United States; in other countries use the local HIV specialist line. [4]

A 28-day course of zidovudine in a study of healthcare workers with needlestick injuries was associated with an 81% reduction in infection, which is the basis for extending the idea to non-occupational exposures, but no randomised trial of PEP after sexual assault exists. [4] Communicate that PEP reduces risk; it does not eliminate it. [5]

Hepatitis B, HPV and other infection prevention

  • Hepatitis B vaccination is recommended after sexual assault if the survivor is not previously vaccinated and the assailant's hepatitis B status is unknown: give the vaccine without hepatitis B immune globulin. [4]
  • If the assailant is known to be HBsAg positive, give both the vaccine and hepatitis B immune globulin to an unvaccinated survivor. [4]
  • Give the first doses at the initial examination; follow-up doses at 1-2 and 4-6 months after the first dose. [4]
  • For survivors previously vaccinated but not post-vaccination tested, a single booster dose is given. [4]
  • HPV vaccination is recommended for female and male survivors aged 9-26 years who are unvaccinated or incompletely vaccinated, because they are at risk of HPV infection, and the vaccine is highly effective; schedule follow-up doses at 1-2 and 6 months after the first dose, or use the two-dose schedule for those who start before age 15. [4]

Follow-up

Follow-up is where much care fails because attendance is poor. [4] Book it before the person leaves.

  • If tests were taken at the first visit, see them within 1 week to discuss results, start or adjust treatment and arrange further care. [4]
  • If initial tests were negative and treatment was not given, re-test for STI 1-2 weeks after the assault, when organisms may have reached detectable levels. [4]
  • For survivors treated at the first visit, re-test only if symptoms develop. [4]
  • If the assailant's infection status cannot be ruled out, repeat syphilis serology at 4-6 weeks and 3 months, and HIV testing at 6 weeks and 3 months. [4]
  • If pregnancy did not occur, start effective contraception of the person's choice and provide it until follow-up. [6]
  • Reassess mental health at every visit, not only at the first. [2]

Obtaining informed consent for the examination and for the release of information to third parties is a crucial part of care. [1] The WHO 2013 and 2003 guidelines both treat consent and confidentiality as clinical acts, not administrative ones. [1][2]

Principles to apply:

  • Consent is specific. Consent to medical examination is not consent to release records to the police. Consent to one set of samples is not consent to all. Ask, explain, document each decision.
  • Capacity. Assess whether the person understands, retains, weighs and communicates their choice. Intoxication, head injury or severe trauma can impair capacity in the acute phase; recheck as the person recovers, and involve a trusted decision-maker only where your law requires it.
  • No coercion by authorities. In many systems police request immediate forensic examination; being a witness is not the same as being a patient. If the person declines, respect that and document. A refusal of evidence collection never means a refusal of care.
  • Children and vulnerable adults. Mandatory reporting applies in many jurisdictions; when in doubt, follow local policy and consult the safeguarding lead. Medico-legal examination and evidence collection in children should be carried out only by trained clinicians. [3]
  • Limits on previous sexual history. Most legal systems restrict the use of a survivor's previous sexual history, including previously acquired STIs, in court. In many jurisdictions an evidentiary privilege protects parts of the examination or record. [4]
  • Privacy. Secure records, limited access, private space, no public discussion. The records may later be needed both for care and for law; store and label them accordingly.
  • Reporting. Know whether your setting has mandatory reporting of sexual assault of adults. In many countries reporting is the survivor's choice for adults and mandatory for children; telling a survivor that reporting is compulsory when it is not is a serious breach of trust. Where possible, arrange an interpreter or advocate and give written information.

Documentation and communication

Good documentation reads as if written by someone who was there and thought about the person:

  • The person's own words, in quotation marks where possible, for how the assault began, what was said and any threats made.
  • A timeline (date and time of arrival, of the assault, of washing or changing, and of the examination).
  • Injuries described, not diagnosed. Size, shape, colour, location using anatomical terms; body maps and photographs with consent. Note where injuries are absent as well.
  • What was examined and what was not. Record refusals without judgement.
  • Specimens. What was collected, when, where, and the chain of custody.
  • Tests ordered, treatment given, advice given, safety plan, referrals made.
  • Interpreter and chaperone names if used.

Clinical descriptions should be factual, neutral and free of opinion about whether the assault happened. The courts, not you, decide whether a crime occurred. [1]

For drug-facilitated or alcohol-related cases, record exact sampling times and transfer to the forensic laboratory promptly. [1]

Escalation and referral

Refer early rather than late, and in parallel with rather than in place of care:

  • Immediate life threats: call emergency services for airway concerns, strangulation with neurological symptoms, significant haemorrhage, head injury or drug-facilitated unconsciousness.
  • Forensic and legal: local sexual assault referral centre, forensic medical examiner, or sexual assault nurse examiner (SANE).
  • Specialist sexual health and HIV: infectious diseases for complex PEP, HIV infection or drug interactions; local HIV specialist or the PEP hotline; sexual health clinic for STI follow-up and HPV and hepatitis B series completion.
  • Reproductive health: women's health or contraception service for copper IUD insertion when not available on site, and for pregnancy options.
  • Mental health and social support: trauma-focused psychologist, sexual assault support service, child and adolescent service, refuge and safety planning, legal advice, interpreter.

Pitfalls

These are the mistakes that quietly damage care and evidence:

  • Treating the examination as proof of the assault, or reassuring that a normal examination rules it out.
  • Performing an intimate examination without consent, or before consent is settled, or by a clinician without training.
  • Forgetting pregnancy risk in someone who does not spontaneously mention contraception.
  • Delaying HIV PEP to finish investigations, or not starting it because the assailant's status is unknown.
  • Giving antimicrobials for prophylaxis without discussing side effects or abstaining, or failing to treat because a culture is still pending.
  • Missing hepatitis B and HPV follow-up doses, which are usually where prophylaxis fails.
  • Documenting "appears consistent with" or other quasi-legal conclusions.
  • Re-taking the story in front of police, family or the same clinician three times, which re-traumatises and can change the record.
  • Assuming that men, people with learning disabilities, older adults and sex workers were not assaulted or do not need prophylaxis.
  • Sending a person home at 3 a.m. with no safety plan, no follow-up and no one to call.

Another common error is to confuse forensic and clinical specimens: a swab taken for STI diagnosis is not the same as an evidence swab, and both may be needed. [1]

Flowchart

Sexual assault: stepwise assessment and care

  1. Receive, make safe and offer first-line supportPrivate space; treat injuries and distress; introduce roles; consent explained separately for each step
  2. Consent obtained?Consent to medical care, forensic exam, photographs, samples and police release are separate
  3. Clinical history and risk assessmentTime of assault; acts; washing/voiding/defecation; pregnancy; contraception; LMP; medications; allergies; HIV/hepatitis B/HPV status; substance use; safety; mental state
  4. Question: Time-critical (all run in parallel with consent)
    • Forensic evidence still collectable

      1. Collect specimensSkin 72 h, mouth 12 h, vagina up to 5 days, anus 48 h; photographs with scale; chain of custody
    • Pregnancy possible

      1. Emergency contraceptionCopper IUD within 5 days (best); levonorgestrel 1.5 mg under 72 h; ulipristal 30 mg under 120 h
    • HIV exposure suspected

      1. HIV PEPWithin 72 h, best 24 h; 28-day 3-drug regimen; baseline creatinine, AST/ALT; HIV test baseline, 6 wk and 3 mo
  5. Baseline testsNAATs for STIs at sites of contact; pregnancy test; serum HIV, hepatitis B, syphilis
  6. Prophylaxis at first visitCeftriaxone 500 mg IM + doxycycline 100 mg twice daily 7 days (+ metronidazole 500 mg twice daily 7 days for women); hepatitis B vaccine; HPV vaccine ages 9-26
  7. DocumentPerson's own words; timeline; injuries with body maps; specimens and chain of custody; consent; advice and referrals
  8. Follow-up booked before leavingWithin 1 week; STI re-testing 1-2 weeks if untreated; syphilis/HIV serology at 4-6 weeks and 3 months; mental health; contraception; safety plan
A teaching outline, not a protocol. Use local pathways and involve the sexual assault referral centre early.

Key points

  • Sexual assault care is health care first: safety, injuries, pregnancy, infection and distress, in a private and non-judgemental setting.
  • First-line support (listening, believing, safety, information, referral) is itself a clinical intervention and starts the process. [2]
  • Forensic specimens are time-critical: skin up to 72 hours, mouth up to 12 hours, vagina up to 5 days, anus up to 48 hours. [3]
  • Emergency contraception: copper IUD within 5 days (most effective); levonorgestrel 1.5 mg by mouth within 72 hours; ulipristal acetate 30 mg by mouth within 5 days and first-line orally at 96-120 hours. [6][7]
  • HIV PEP, when indicated, must start as soon as possible and no later than 72 hours (preferably 24 hours), with a 28-day three-drug regimen (CDC 2025 preferred regimens: bictegravir/emtricitabine/tenofovir alafenamide, or dolutegravir plus tenofovir plus emtricitabine/lamivudine). [4][5]
  • Empiric prophylaxis after assault: ceftriaxone 500 mg intramuscularly, doxycycline 100 mg by mouth twice daily for 7 days, and metronidazole 500 mg by mouth twice daily for 7 days for women. [4]
  • Hepatitis B vaccination (without hepatitis B immune globulin unless the assailant is known HBsAg positive) and HPV vaccination aged 9-26 years are started at the first visit with scheduled follow-up doses. [4]
  • Consent, confidentiality and reporting are clinical duties: consent for each step is separate, and child and vulnerable-adult safeguards follow local law. [1]
  • Document in the person's own words, with body maps; do not offer opinions on whether a crime occurred. [1]
  • A normal examination does not exclude assault; injuries after assault are often absent.

Check yourself

Answer each one in your head first, then open the answer.

  1. A 24-year-old woman presents 5 hours after vaginal assault by an unknown man. She has minor bleeding and is distressed but stable. What are the time-critical actions before she leaves?

    Show answerHide answer

    First-line support and consent; a history and safety assessment; pregnancy and STI testing; emergency contraception (prefer copper IUD, or oral EC if declined or delayed); empiric STI prophylaxis; HIV risk assessment with PEP if indicated, started within 24-72 hours; forensic specimens while the window is still open (skin up to 72 h, vagina up to 5 days); first doses of hepatitis B and, if unvaccinated and aged 9-26, HPV vaccines; safety planning; and booking follow-up within 1 week. The reason PEP cannot wait for results is that efficacy falls with every hour. Every step is documented without a diagnostic conclusion about consent or rape. [3][5]

  2. How would you differ for a 24-year-old man who presents 60 hours after receptive anal assault by a man whose HIV status is unknown, but who is otherwise well?

    Show answerHide answer

    Male survivors need the same care. Time windows make this a late but still in-window presentation: HIV PEP must be started now, within the 72-hour cut-off, ideally the first dose given before any further investigation. STI testing and empiric prophylaxis use the male regimen (ceftriaxone 500 mg IM plus doxycycline 100 mg by mouth twice daily for 7 days). Forensic samples from anus fall within 48 hours, so they may still be collectable. Renal and liver function should be checked at baseline, as should HIV, syphilis and hepatitis B. Follow-up includes HIV testing at 6 weeks and 3 months, and counsel about PrEP once PEP is complete. [3][4] [5]

  3. A survivor declines forensic examination but accepts medical care. Is that a problem, and what do you do?

    Show answerHide answer

    No. Consent is specific. Provide all medical care, prophylaxis and follow-up; record the refusal of forensic examination without judgement and with the person's own words about why. If she changes her mind later, samples taken within windows may remain collectable but the quality falls. Explain the windows simply, check safety and access, and never condition care on participation in the legal process. The person's health remains the priority even when evidence cannot be gathered.

  4. Why is a 30 mg dose of ulipristal acetate rather than levonorgestrel preferred when the assault happened 4 days ago?

    Show answerHide answer

    Levonorgestrel 1.5 mg is licensed for under 72 hours and may be used 72-96 hours off label with decreasing efficacy, and it is ineffective once ovulation has occurred. Ulipristal acetate 30 mg is licensed for up to 120 hours (5 days) and is more effective than levonorgestrel; it is the recommended first-line oral emergency contraception for intercourse 96-120 hours earlier. The copper IUD remains the most effective option overall. If a survivor declines an IUD, ulipristal acetate is the better oral choice at 4 days. Body weight and BMI modify efficacy for oral methods, so individualise. [6][7]

  5. You examine a survivor 36 hours after assault and find no genital injury. Can you document that assault is unlikely?

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    No. Absence of injury does not exclude assault; many assaults leave no visible injury, and injuries may appear days later or never. Document exactly what was found and what was not (site and examination type), the time elapsed, and the person's own words. Offer follow-up examination if bruising becomes visible. Do not include opinions on the likelihood of assault in the medical record; that is a matter for the legal system. Clinical neutrality protects both the survivor and any later proceedings.

  6. A woman reports sexual assault 10 days ago. Which time-critical interventions are now outside window, and what remains possible?

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    Forensic specimens from skin, mouth, vagina and anus are outside their ideal windows, although some samples and injuries may still be recorded. Emergency contraception and HIV PEP windows have closed, so treatment shifts to detecting pregnancy and infection: pregnancy test now and at follow-up if no period; STI testing and treatment; HIV and syphilis baseline with tests repeated at 6 weeks and 3 months; hepatitis B and HPV vaccination series; and careful mental health and safety assessment. Document the delayed presentation without blame, and explain why some time-sensitive options are no longer effective in plain language. [3][4]

Emergency contraception; contraception; sexually transmitted infections; HIV prevention and pre-exposure prophylaxis; post-exposure prophylaxis for HIV; hepatitis B infection; human papillomavirus; trauma and post-traumatic stress in psychiatry; paediatric safeguarding; medicolegal documentation.

References

  1. World Health Organization. Guidelines for medico-legal care for victims of sexual violence. World Health Organization, Geneva, 2003. Accessed .
  2. World Health Organization. Responding to intimate partner violence and sexual violence against women: WHO clinical and policy guidelines. World Health Organization, Geneva, 2013. Accessed .
  3. World Health Organization. Caring for women subjected to violence: A WHO curriculum for training health-care providers. World Health Organization, Geneva, 2019. Accessed .
  4. Workowski KA, Bachmann LH, Chan PA, et al. Sexually Transmitted Infections Treatment Guidelines, 2021: Sexual Assault and Abuse and STIs - Adolescents and Adults. MMWR Recomm Rep 2021;70(4):1-187. Accessed .
  5. Tanner MR, et al. Antiretroviral Postexposure Prophylaxis After Sexual, Injection-Drug Use, or Other Nonoccupational Exposure to HIV: CDC Recommendations, United States, 2025. MMWR Recomm Rep 2025;74(1):1-56. Accessed .
  6. College of Sexual and Reproductive Healthcare (CoSRH, formerly FSRH). Emergency contraception: clinical guidance (March 2017, amended July 2023). CoSRH, London. Accessed .
  7. National Institute for Health and Care Excellence. Emergency contraception (treatment summary). British National Formulary, London. Accessed .

Educational content for medical students and doctors. It is not a substitute for clinical judgement or local guidelines.